Four Core Principles of Cleanroom Contamination Control - Nanjing Expansion Technology Co., Ltd.

Release time:

2025-03-26 14:41

Cleanrooms play an irreplaceable and central role in many industries with extremely high requirements for environmental cleanliness, such as electronics, pharmaceuticals, and medicine. The cleanliness of a cleanroom depends not only on professional design, construction processes, and advanced equipment, but also on a scientific management system. Effective control of pollution sources is a key element in maintaining good cleanroom cleanliness.

Nanjing Expansion Technology, as a professional laboratory construction service provider, now provides an analysis of the four core principles of cleanroom pollution control.

I. Classification of Cleanroom Pollution Sources
Cleanroom pollution sources can be divided into two categories: external pollution and internal pollution.

External pollution mainly refers to pollutants that penetrate from the external environment, including: air conditioning air supply systems, substances that seep through building gaps, attachments on personnel work clothes, substances released from duct materials, and process water/solvents and other media. These external pollution sources may Enter the cleanroom through air flow or material transfer.

Internal pollution originates from the operation process within the cleanroom, mainly including: products of production equipment operation, emissions from staff activities, tool friction debris, by-products of processing and manufacturing, materials from work surfaces, and substances released from packaging materials. These internal pollution sources continuously generate pollution particles during daily production.

II. Four Principles of Cleanroom Pollution Control

Block External Pollution Penetration
Cleanrooms require multiple protective barriers: maintain a stable positive pressure inside the room (>5Pa), forming an air pressure isolation layer; strictly control the airtightness of the building during construction to eliminate structural gaps; materials must undergo cleaning and disinfection procedures before entering the cleanroom; equip a high-efficiency air filtration system to ensure the air supply cleanliness meets standards.。

Suppress Internal Pollution Generation
Cleanroom building materials should use low-dust-releasing materials, and the floor should use anti-static integral treatment; implement a regular maintenance system for production equipment to reduce operational pollution; staff must strictly follow cleanroom behavioral standards, wear professional cleanroom clothing, and change it regularly; dedicated tools and equipment must meet cleanroom usage standards.

Eliminate Pollution Accumulation Risks
Cleanrooms use a no-dead-angle arc design to avoid particle accumulation; establish a graded cleaning system, including daily wiping, periodic deep cleaning, and comprehensive sterilization procedures; equipment layout should reserve sufficient maintenance space to ensure cleanliness accessibility.

Enhance Particle Removal Efficiency
Set the corresponding ventilation frequency according to the cleanroom level, and ensure air circulation efficiency through reasonable airflow organization design; equip local exhaust devices in key pollution areas; use an intelligent monitoring system to adjust airflow parameters in real-time to maintain the optimal cleanliness state.

Cleanroom pollution control is a core element in ensuring the safety of the production environment. Nanjing Expansion Technology, with its professional cleanroom construction qualifications and rich project experience, provides full-process services covering planning and design, construction, and testing and certification. We strictly followISO cleanroom standards, and through the systematic implementation of the "external prevention-internal control-cleaning-purification" four-dimensional control system, we create high-standard cleanroom environments for scientific research institutions, testing institutions, and biopharmaceutical companies.

Nanjing Expansion Technology is always committed to the innovative application of cleanroom technology. By combining scientific management methods and advanced technological equipment, we help achieve precise control of the scientific research environment and provide reliable cleanroom assurance for our users.

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